Abnormal glutamatergic and serotonergic connectivity in visual snow syndrome and migraine with aura.

Our results show that glutamate and serotonin are involved in brain connectivity alterations in areas of the visual, salience and limbic systems in VSS. Importantly, altered serotonergic connectivity is independent of migraine in VSS, and simultaneously comparable to that of migraine with aura, highlighting a shared biology between the disorders. This article is protected by copyright. All rights reserved.