DNA Methylation Analysis of the SHOX2 and RASSF1A Panel Using Cell-Free DNA in the Diagnosis of Malignant Pleural Effusion.

Nana ZhangZichen LiuKun LiXuya XingChaolian LongFangchao LiuBin SheNan-Ying Che

Published in: Journal of oncology (2023)

methylation detection of PE-cfDNA could be a potentially effective complementary tool for cytology in the process of differential diagnosis. In summary, PE-cfDNA could be used as a promising non-invasive analyte for the auxiliary diagnosis of MPE.

Keyphrases

dna methylation
genome wide
gene expression
high grade
fine needle aspiration
loop mediated isothermal amplification
real time pcr
quantum dots