Use of existing electronic health care databases to evaluate medication safety in pregnancy: Triptan exposure in pregnancy as a case study.

Akeem A YusufVictoria ChiaFei XueDaniel D MikolLisa BollingerCharles Cangialose

Published in: Pharmacoepidemiology and drug safety (2018)

These results confirm broad agreement between the database analysis and the registry regarding the safety of triptans during pregnancy. Of note, the number of triptan-exposed pregnancies identified in this large US database was about 7-fold that included in the prospective registry over the same time frame. The findings of this study support an approach of using existing health care database (s) in the post-approval assessment of medication exposure in pregnancy.

Keyphrases

healthcare
preterm birth
adverse drug
pregnancy outcomes
gestational age
emergency department
machine learning
social media
deep learning
data analysis