Predicting and improving outcomes of transcatheter aortic valve replacement in older adults and the elderly.
Antonio Giulio BrunoLaura SantonaTullio PalmeriniNevio TaglieriCinzia MarrozziniGabriele GhettiMateusz OrzalkiewiczNazzareno GalièFrancesco SaiaPublished in: Expert review of cardiovascular therapy (2020)
In the next future TAVR will probably represent the first treatment option for patients affected by aortic valve stenosis who are candidates to receive a biological valve. Continuous refinement of TAVR devices has been key to allow safer and most effective procedures and further progress is expected. Development of new techniques and devices, such as ultrasound-guided puncture and intravascular lithotripsy, will expand safety and eligibility to transfemoral procedures. Effective preemptive measures for coronary occlusion have been developed. Open issues include cerebral protection, re-access to coronary arteries, post-procedural management, and therapy.
Keyphrases
- transcatheter aortic valve replacement
- aortic valve
- aortic stenosis
- transcatheter aortic valve implantation
- aortic valve replacement
- ejection fraction
- ultrasound guided
- coronary artery
- coronary artery disease
- newly diagnosed
- end stage renal disease
- prognostic factors
- subarachnoid hemorrhage
- physical activity
- chronic kidney disease
- heart failure
- current status
- brain injury
- atrial fibrillation
- patient reported outcomes
- stem cells
- insulin resistance
- skeletal muscle
- replacement therapy