Sleep Apnea in Idiopathic Pulmonary Fibrosis: A Molecular Investigation in an Experimental Model of Fibrosis and Intermittent Hypoxia.

Liasmine HaineJuliette BravaisCéline-Hivda YegenJean-Francois BernaudinDominique MarchantCarole PlanèsNicolas Voituron Emilie Boncoeur

Published in: Life (Basel, Switzerland) (2021)

Our results showed that IH exacerbates BLM-induced lung fibrosis more markedly when IH precedes lung fibrosis induction, and that this is associated with an enhancement of ER stress markers.

Keyphrases

idiopathic pulmonary fibrosis
sleep apnea
obstructive sleep apnea
positive airway pressure
high glucose
liver fibrosis
endothelial cells
interstitial lung disease
high intensity
single molecule