Long noncoding RNA 01534 maintains cancer stemness by downregulating endoplasmic reticulum stress response in colorectal cancer.
Momoko IchiharaHidekazu TakahashiNaohiro NishidaCristina IvanDaisuke OkuzakiYuhki YokoyamaMasahisa OhtsukaNorikatsu MiyoshiMamoru UemuraShinji TanakaGeorge Adrian CalinMasaki MoriYuichiro DokiHidetoshi EguchiHirofumi YamamotoPublished in: Annals of gastroenterological surgery (2022)
This is the first report on LINC01534 in human cancer. Our findings suggest that LINC01534 may be an important modulator of the maintenance of cancer stemness and suppression of the ER stress response, and that it could be a novel prognostic factor in CRC.