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Advancements in Fabrication and Application of Chitosan Composites in Implants and Dentistry: A Review.

Fariborz SharifianjaziSamad KhaksarAmirhossein EsmaeilkhanianLeila BazliSara EskandarinezhadPeyman SalahshourFarnaz SadeghiSadegh RostamniaSeyed Mohammad Vahdat
Published in: Biomolecules (2022)
Chitosan is a biopolymer that is found in nature and is produced from chitin deacetylation. Chitosan has been studied thoroughly for multiple applications with an interdisciplinary approach. Antifungal antibacterial activities, mucoadhesion, non-toxicity, biodegradability, and biocompatibility are some of the unique characteristics of chitosan-based biomaterials. Moreover, chitosan is the only widely-used natural polysaccharide, and it is possible to chemically modify it for different applications and functions. In various fields, chitosan composite and compound manufacturing has acquired much interest in developing several promising products. Chitosan and its derivatives have gained attention universally in biomedical and pharmaceutical industries as a result of their desired characteristics. In the present mini-review, novel methods for preparing chitosan-containing materials for dental and implant engineering applications along with challenges and future perspectives are discussed.
Keyphrases
  • drug delivery
  • wound healing
  • hyaluronic acid
  • working memory
  • oxidative stress
  • gold nanoparticles
  • reduced graphene oxide