Pharmacodynamics and pharmacokinetics of DWP14012 (fexuprazan) in healthy subjects with different ethnicities.
Jun Gi HwangInseung JeonSun Ae ParkAreum LeeKyung-Sang YuIn-Jin JangSeungHwan LeePublished in: Alimentary pharmacology & therapeutics (2020)
Gastric acid suppression by DWP14012 was similar among the Korean, Caucasian and Japanese subjects in this study, and the PK, PK-PD relationships and safety were also similar among the three ethnicities. DWP14012 could be used without consideration of ethnicity.
Keyphrases