Blockade of the 5-HT transporter contributes to the behavioural, neuronal and molecular effects of cocaine.
Linda D SimmlerAllison M J AnackerMichael H LevinNina M VaswaniPaul J GreschAlex G NackenoffNoelle C AnastasioSonja J StutzKathryn A CunninghamJing WangBing ZhangL Keith HenryAdele StewartJeremy Veenstra-VanderWeeleRandy D BlakelyPublished in: British journal of pharmacology (2017)
Our studies reveal distinct SERT contributions to cocaine action, reinforcing the possibility of targeting specific aspects of cocaine addiction by modulation of 5-HT signalling.