Prioritizing sufficient dose to gross tumor volume over normal tissue sparing in intensity-modulated radiotherapy treatment of T4 nasopharyngeal carcinoma.

Yanyan Chen Qu-Xia ZhangTianzhu LuCairong HuJingfeng ZongYun XuWei ZhengLisha ChenSenan LinSufang QiuLuying XuJianji Pan Qiaojuan Guo Shao-Jun Lin

Published in: Head & neck (2023)

Our retrospective review showed that its feasible to maximize gross tumor volume dose coverage while exceeding most CNS OAR constraint standards, with ideal local control and no obvious increase of craniocerebral toxicity.

Keyphrases

early stage
children with cerebral palsy
oxidative stress
blood brain barrier
healthcare
locally advanced
squamous cell carcinoma
combination therapy