Early Clinical Variables Associated With Refractory Convulsive Status Epilepticus in Children.
Katrina PearisoRavindra AryaTracy A GlauserNicholas S AbendCristina Barcia AguilarMarta Amengual-GualAnne AndersonBrian L AppavuJames Nicholas BrentonJessica CarpenterKevin E ChapmanJustice ClarkWilliam D GaillardMarina Gaínza-LeinJoshua GoldsteinHoward P GoodkinZachary M GrinspanRejean M GuerrieroPaul S HornLinda HuhRobert KahoudSarah A KelleyEric H KossoffKush KapurYi-Chen LaiB Oyinkan MarquisTiffani McDonoughMohamad A MikatiLindsey MorganEdward J NovotnyAdam P OstendorfEric T PayneJuan PiantinoJames RivielloTristan T SandsCarl E StafstromRobert Charles TaskerDmitry TchapyjnikovAlejandra Vasquez-AvilaMark S WainwrightAngus WilfongKorwyn WilliamsTobias Loddenkempernull nullPublished in: Neurology (2023)
Time to initial BZD or second-line ASM was not associated with progression to RSE in our cohort of patients with rESE. A family history of seizures and a prescription for rectal diazepam were associated with a decreased likelihood of progression to RSE. Early attainment of these variables may help care for pediatric rESE in a more patient-tailored manner. COE: This study provides class II evidence that patient and clinical factors may predict RSE in children with convulsive seizures.