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Relationship between amikacin pharmacokinetics and biological parameters associated with organ dysfunction: a case series study of critically ill patients with intra-abdominal sepsis.

Bita ShahramiAida Sefidani ForoughSeyedeh Sana KhezrniaFarhad NajmeddinAmir Ahmad ArabzadehMohammad Reza RouiniAtabak NajafiMojtaba Mojtahedzadeh
Published in: European journal of hospital pharmacy : science and practice (2021)
ESR and serum lactate were identified as useful predictors of amikacin pharmacokinetics in critically ill patients with intra-abdominal sepsis and may help guide the selection of appropriate empirical dosing.
Keyphrases
  • acute kidney injury
  • intensive care unit
  • septic shock
  • oxidative stress