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Neurofilament Light Chain as a Biomarker of Global Cognition in Individuals With Possible Vascular Mild Cognitive Impairment.

Amish GaurDamien GallagherNathan HerrmannJinghan Jenny ChenSusan MarzoliniPaul OhYutaka AmemiyaArun SethAlex KissKrista L Lanctôt
Published in: Journal of geriatric psychiatry and neurology (2024)
Plasma NfL correlates with global cognition at baseline in individuals with vMCI, and is associated with decline in global cognition during CR. Our findings increase understanding of NfL and neurobiological mechanisms associated with cognitive decline in vMCI.
Keyphrases
  • mild cognitive impairment
  • cognitive decline
  • cerebrospinal fluid