Modeling Blast Crisis Using Mutagenized Chronic Myeloid Leukemia-Derived Induced Pluripotent Stem Cells (iPSCs).
Jusuf ImeriChristophe DesterkePaul MarcouxGladys TelliamSafa SanekliSylvain BarreauYücel ErbilginTheodoros LatsisPatricia HuguesNathalie SorelEmilie CayssialsJean-Claude ChomelAnnelise Bennaceur-GriscelliAli G TurhanPublished in: Cells (2023)
iPSCs are a valuable tool to model CML progression and to identify new targets. Here, we show the relevance of CD25 identified in the iPSC model as a marker of CML progression.