Monocytes accumulate in the airways of children with fatal asthma.

Ibon Eguíluz-GraciaKristiina MalmstromSinan Ahmed DheyauldeenJouko LohiAntti SajantilaRagnhild AaløkkenArvind Y M SundaramGregor D GilfillanMika MakelaEspen Sønderaal BækkevoldFrode L Jahnsen

Published in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2018)

Monocytes accumulated in the lungs of children and adolescents with fatal asthma attack. This finding strongly suggests that monocytes are directly involved in the immunopathology of asthma and that these pro-inflammatory cells are potential targets for therapy.

Keyphrases

chronic obstructive pulmonary disease
lung function
allergic rhinitis
dendritic cells
peripheral blood
induced apoptosis
cystic fibrosis
young adults
cell cycle arrest
air pollution
stem cells
risk assessment
mesenchymal stem cells
pi k akt