LncRNA HOTAIR regulates the PI3K/AKT pathway via the miR-126-3p/PIK3R2 axis to participate in synovial angiogenesis in rheumatoid arthritis.

Published in: Immunity, inflammation and disease (2023)

LncRNA HOTAIR has the potential to activate the PI3K/AKT pathway, likely through the regulatory axis involving miR-126-3p/PIK3R2, consequently contributing to synovial angiogenesis in RA.

Keyphrases

rheumatoid arthritis
endothelial cells
vascular endothelial growth factor
disease activity
long non coding rna
long noncoding rna
ankylosing spondylitis
wound healing
interstitial lung disease
transcription factor
systemic lupus erythematosus
risk assessment
idiopathic pulmonary fibrosis