Resistance to first-line antibiotic therapy among patients with uncomplicated acute cystitis in Melbourne, Australia: prevalence, predictors and clinical impact.
Stephanie J CurtisJason C KwongYee Lin ChaungDanielle MazzaCalum J WalshKyra Y ChuaAndrew J StewardsonPublished in: JAC-antimicrobial resistance (2023)
Resistance to trimethoprim is common in uncomplicated UTIs in Australia but may not impact clinical outcomes. Further research is warranted on the appropriateness of trimethoprim as empirical therapy, particularly for patients with antimicrobial resistance risk factors.