Reliable radiosynthesis of 4-[10B]borono-2-[18F]fluoro-L-phenylalanine with quality assurance for boron neutron capture therapy-oriented diagnosis.

Kiichi IshiwataRyoichi EbinumaChuichi WatanabeKunpei HayashiJun Toyohara

Published in: Annals of nuclear medicine (2018)

L-[18F]FBPA injection was reliably prepared by the electrophilic fluorination of L-BPA with [18F]AcOF followed by HPLC separation with 1 mM phosphate-buffered saline.

Keyphrases

ms ms
simultaneous determination
positron emission tomography
pet imaging
liquid chromatography
mass spectrometry
ultrasound guided
tandem mass spectrometry
bone marrow
high resolution