Distinct HLA and non-HLA associations in different subtypes of ANCA-associated vasculitides in North India.

Jagdeep SinghAman SharmaLekha RaniNavchetan KaurShashi AnandBiman SaikiaSaket JhaRitambhra NadaRanjana Walker Minz

Published in: International journal of rheumatic diseases (2020)

The study indicated strong genetic associations were linked with PR3 antineutrophil cytoplasmic antibody specificity and it appears that PR3-AAV and MPO-AAV have distinct genetic backgrounds.

Keyphrases

genome wide
gene therapy
copy number
dna methylation
gene expression
tertiary care