Resolution of dominant patient-reported outcome at end of induction predicts clinical and endoscopic remission in Crohn's disease.
Emily Chu Lee WongParambir S DulaiJohn K MarshallVipul JairathWalter ReinischNeeraj NarulaPublished in: Alimentary pharmacology & therapeutics (2022)
Post-induction resolution of dominant PRO, but not clinical or PRO2 response, was strongly associated with 1-year endoscopic and clinical remission. Resolution of dominant baseline PRO after induction therapy may be informative for 1-year outcomes. Further validation is required.