Targeting Ferroptosis-Elicited Inflammation Suppresses Hepatocellular Carcinoma Metastasis and Enhances Sorafenib Efficacy.

Ming Mu Chun-Xiang Huang Chuang Qu Pei-Lin Li Xiang-Ning Wu Wudexin Yao Chu Shen Rucheng Huang Chao-Chao Wan Zhi-Wei Jian Limin Zheng Rui-Qi Wu Xiang-Ming Lao Dong-Ming Kuang

Published in: Cancer research (2024)

Ferroptosis induces a favorable tumor microenvironment and supports liver cancer progression by stimulating an inflammatory cellular network that can be targeted to suppress metastasis and improve the efficacy of sorafenib.

Keyphrases

cell death
oxidative stress
cancer therapy
signaling pathway
drug delivery