Epigenetic aging differences between Wichí and Criollos from Argentina: Insights from genomic history and ecology.

Vincenzo IannuzziStefania SarnoMarco Sazzini Paolo Abondio Claudia SalaMaria Giulia BacaliniDavide GentiliniLuciano CalzariFederica MasciottaPaolo GaragnaniGastone CastellaniEdgardo MorettiMaria Cristina DassoFederica SeviniZelda Alice FranceschiClaudio FranceschiDavide PettenerDonata Luiselli Cristina Giuliani

Published in: Evolution, medicine, and public health (2023)

Overall, our study suggests that while the genomic history may partially account for the observed epigenetic differences, non-genetic factors, such as lifestyle and ecological factors, play a substantial role in the variability of epigenetic estimators, thereby contributing to variations in human epigenetic aging.

Keyphrases

dna methylation
gene expression
copy number
genome wide
endothelial cells
cardiovascular disease
weight loss