Dynamic thiol-disulfide homeostasis as an oxidative stress marker in ankylosing spondylitis and undifferentiated spondyloarthropathy.
Cemaleddin ÖztürkŞükran ErtenMurat AlışıkIsmail DoganGüniz Yanık ÜstünerSalim NeşelioğluOzcan ErelPublished in: Turkish journal of medical sciences (2021)
The thiol-disulfide balance is disturbed in favor of disulfide in SpA patients compared to healthy volunteers. Native and total thiol measurements correlate with acute phase reactants and might be used to monitor disease activity. Anti-TNF therapy might control the oxidative degenerative process better than the conventional DMARD in SpA patients.
Keyphrases
- ankylosing spondylitis
- disease activity
- end stage renal disease
- rheumatoid arthritis
- oxidative stress
- ejection fraction
- newly diagnosed
- systemic lupus erythematosus
- chronic kidney disease
- peritoneal dialysis
- prognostic factors
- stem cells
- patient reported outcomes
- mesenchymal stem cells
- signaling pathway
- juvenile idiopathic arthritis
- patient reported
- smoking cessation