Age-dependent VDR peak DNA methylation as a mechanism for latitude-dependent multiple sclerosis risk.

Lawrence T C OngStephen D SchibeciNicole L FewingsDavid R BoothGrant P Parnell

Published in: Epigenetics & chromatin (2021)

These results suggest vitamin D exposure at critical periods during development may contribute to latitude-related differences in autoimmune disease incidence.

Keyphrases

multiple sclerosis
dna methylation
genome wide
white matter
risk factors
gene expression
copy number