Spontaneous head twitches in aged rats: behavioral and molecular study.

Alicja Zakrzewska-Sito Przemyslaw Bienkowski Marcin Kolaczkowski Irena Nalepa Agnieszka Zelek-Molik Adam Bielawski Katarzyna Chorążka Julita Kuczyńska Paweł Mierzejewski

Published in: Psychopharmacology (2022)

SHT appears in some aging rats (about 50%) and is permanent over time and specific to individuals. The 5-HT2A receptor strongly controls SHT. HSHT animals can be a useful animal model for studying 5-HT2A receptor ligands.

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