MNAT1 promotes proliferation and the chemo-resistance of osteosarcoma cell to cisplatin through regulating PI3K/Akt/mTOR pathway.

Chensheng QiuWeiliang SuNana ShenXiaoying QiXiaolin WuKai WangLin LiZhu GuoHao TaoGuanrong WangBohua ChenHongFei Xiang

Published in: BMC cancer (2020)

Taken together, the data of the present study demonstrate a novel molecular mechanism of MNAT1 involved in the formation of DDP resistance of OS cells.

Keyphrases

induced apoptosis
signaling pathway
single cell
photodynamic therapy
cell cycle arrest
cell therapy
electronic health record
stem cells
big data
machine learning
oxidative stress
drug delivery
cancer therapy
artificial intelligence
data analysis