Effects of CB1 receptor negative allosteric modulator Org27569 on oxycodone withdrawal symptoms in mice.

Rhianne L SciclunaNicholas A EverettConnie J BadolatoBianca B WilsonMichael T Bowen

Published in: Psychopharmacology (2024)

Org27569 effects on negative affective-like symptoms were confounded by locomotor effects and effects on gastrointestinal motility were not opioid withdrawal specific. Further studies are needed in a model that produces a more pronounced protracted withdrawal syndrome.

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