Age Differences in Core Symptoms and Symptom Relationships in Patients with Irritable Bowel Syndrome: A Network Analysis.
Pei-Lin YangKendra J KampRobert L BurrHsin-Yi Jean TangAdrian DobraRobert J ShulmanMargaret H HeitkemperPublished in: The American journal of gastroenterology (2023)
Network analysis suggests fatigue is a critical target for symptom management in adults with IBS, regardless of age. Comorbid anxiety is likely an important treatment focus for young adults with IBS. Rome V Criteria update could consider the importance of intestinal gas and bloating symptoms. Additional replication with larger diverse IBS cohorts is warranted to verify our results.