Analysis of Signal Transduction Pathways Downstream M2 Receptor Activation: Effects on Schwann Cell Migration and Morphology.

Elisabetta BotticelliMichael Sebastian Salazar IntriagoRoberta Piovesana Ada Maria Tata

Published in: Life (Basel, Switzerland) (2022)

The data obtained demonstrated that M2 receptor activation in addition to the canonical Gi protein-coupled pathway modulates noncanonical pathways involving the mTORC1 complex and other kinases whose activation may contribute to the inhibition of SC proliferation and migration and address SC differentiation.

Keyphrases

cell migration
binding protein
big data
amino acid
peripheral nerve
protein protein