FDA-approved cannabidiol [Epidiolex ® ] alleviates Gulf War Illness-linked cognitive and mood dysfunction, hyperalgesia, neuroinflammatory signaling, and declined neurogenesis.
Maheedhar KodaliLeelavathi N MadhuVenkata Sai Vashishta KollaSahithi AttaluriCharles HuardYogish SomayajiBing ShuaiChase JordanXiaolan RaoSanath ShettyAshok K ShettyPublished in: Military Medical Research (2024)
) has been shown to effectively alleviate cognitive and mood impairments as well as hyperalgesia associated with chronic GWI. Importantly, the improvements observed in rats with chronic GWI in this study were attributed to the ability of CBD to significantly suppress signaling pathways that perpetuate chronic neuroinflammation.