Completion of Pembrolizumab in Advanced Non-Small Cell Lung Cancer-Real World Outcomes After Two Years of Therapy (COPILOT).
Andrew FantoniLydia WarburtonBenjamin SolomonMarliese AlexanderMeghana MaddulaLauren Julia BrownInes Pires da SilvaAdnan NagrialFarah Abu Al-HialMalinda ItchinsNick PavlakisSamantha BowyerPublished in: Clinical lung cancer (2024)
Patients completing two-years of pembrolizumab for NSCLC in an Australian cohort had high rates of KRAS mutation and PD-L1 expression; a proportion had brain metastases and treated oligoprogression. Progression post pembrolizumab was higher in PD-L1 TPS < 1% and in those without complete response.