Drug-Drug Interactions and Their Association with Adverse Health Outcomes in the Older Community-Dwelling Population: A Prospective Cohort Study.

John E Hughes Kathleen E Bennett Caitriona Cahir

Published in: Clinical drug investigation (2024)

We found a two-fold increase in DDI prevalence between wave 1 and 2. DDI exposure was associated with increasing ADEs and declining HRQoL at 2-year follow-up. Common DDIs involved anticoagulants, cardiovascular and antimicrobial drugs, which should be targeted for medicine optimisation.

Keyphrases

community dwelling
adverse drug
risk factors
staphylococcus aureus
cancer therapy
drug induced
emergency department
drug delivery
physical activity
electronic health record