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Combination of an Autoantibody Panel and Alpha-Fetoprotein for Early Detection of Hepatitis B Virus-Associated Hepatocellular Carcinoma.

Yajing ShenJiajun ChenJinyu WuTiandong LiChuncheng YiKeyan WangPeng WangChangqing SunHua Ye
Published in: Cancer prevention research (Philadelphia, Pa.) (2024)
We developed a robust diagnostic panel for identifying patients with HBV-HCC from patients with CHB. This autoantibody panel provided superior diagnostic performance for HBV-HCC at an early stage and/or with negative AFP results. Our findings suggest that AFP and the autoantibody panel may be independent but complementary biomarkers for HBV-HCC detection.
Keyphrases
  • hepatitis b virus
  • early stage
  • liver failure
  • squamous cell carcinoma
  • lymph node
  • sentinel lymph node
  • neoadjuvant chemotherapy
  • quantum dots