Functional analysis of granulocyte and monocyte subpopulations in neonates.

Ines HeggeFerry NiepelAnja LangeAntje VogelgesangMatthias HeckmannJohanna Ruhnau

Published in: Molecular and cellular pediatrics (2019)

Differentially regulated granulocyte and monocyte subpopulations indicate a unique state of neonatal immunity to fight infections and prevent dysregulation. Further studies are needed to investigate the role of reduced granulocytic ROS formation and reduced monocytic HLA-DR in active disease.

Keyphrases

peripheral blood
dendritic cells
endothelial cells
cell death
dna damage
transcription factor
reactive oxygen species
recombinant human
immune response
oxidative stress