Hypoxia in the pulmonary vein increases pulmonary vascular resistance independently of oxygen in the pulmonary artery.

Sigridur Olga MagnusdottirCarsten SimonsenDan Stieper KarbingBodil Steen RasmussenBenedict Kjærgaard

Published in: Animal models and experimental medicine (2024)

The impact of hypoxia occurs from the alveolar level and forward with the blood flow. The experiments indicated that the regulation of PVR is mediated from the venous side.

Keyphrases

pulmonary artery
blood flow
pulmonary hypertension
coronary artery
pulmonary arterial hypertension
endothelial cells