Delta opioid peptide [D-ala2, D-leu5]-Enkephalin's ability to enhance mitophagy via TRPV4 to relieve ischemia/reperfusion injury in brain microvascular endothelial cells.
Zhongfang DengXiaoyu ChenRan ZhangLingchao KongYang FangJizheng GuoBing ShenLesha ZhangPublished in: Stroke and vascular neurology (2024)
DADLE can promote mitophagy in BMECs through TRPV4, improving mitochondrial function and relieving I/R injury.