Roflumilast, a phosphodiesterase 4 inhibitor, attenuates cadmium-induced renal toxicity via modulation of NF-κB activation and induction of NQO1 in rats.
Mohd Nazam AnsariR I AlolietM A GanaieT H Khannull Najeeb-Ur-RehmanF ImamAbubaker M HamadPublished in: Human & experimental toxicology (2019)
In conclusion, ROF treatment showed protective effect against renal damage and increased oxidative stress induced by Cd administration.