Spray-Dried and Spray-Freeze-Dried Powder Formulations of an Anti-Interleukin-4Rα Antibody for Pulmonary Delivery.

Harry W PanHan Cong SeowJason C K LoJinlin GuoLingqiao ZhuSusan W S LeungChenghai ZhangJenny Ka Wing Lam

Published in: Pharmaceutical research (2022)

The findings of this study establish the feasibility of developing an inhaled dry powder formulation of an anti-IL-4R antibody using spray drying and spray freeze drying techniques with potential for the treatment of severe asthma.

Keyphrases

pulmonary hypertension
drug delivery
cystic fibrosis
risk assessment
human health