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Exploration of the Key Proteins of High-Grade Intraepithelial Neoplasia to Adenocarcinoma Sequence Using In-Depth Quantitative Proteomics Analysis.
Yin Zhang
Chun-Yuan Li
Meng Pan
Jing-Ying Li
Wei Ge
Lai Xu
Yi Xiao
Published in:
Journal of oncology (2021)
ECM-related biological processes and pathways are typical features of the HIN-AC sequence. SERPINH1 and P3H1 might be the key proteins in this sequence and be related to ECM remodeling and immune suppression status in CRC.
Keyphrases
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high grade
low grade
squamous cell carcinoma
mass spectrometry
extracellular matrix
high resolution
optical coherence tomography
locally advanced
radiation therapy