Immunosuppression by monocytic myeloid-derived suppressor cells in patients with pancreatic ductal carcinoma is orchestrated by STAT3.

Rosalinda TrovatoAlessandra FioreSara SartoriStefania CanèRosalba GiugnoLuciano CascioneSalvatore PaiellaRoberto SalviaFrancesco De SanctisOrnella PoffeCristina AnselmiFrancesca HoferSilvia SartorisGeny PiroCarmine CarboneVincenzo BronteRita LawlorSamantha SolitoLaura PintonSusanna MandruzzatoClaudio BassiAldo ScarpaVincenzo BronteStefano Ugel

Published in: Journal for immunotherapy of cancer (2019)

MDSC analysis aids in defining the immune landscape of PDAC patients for a more appropriate diagnosis, stratification and treatment.

Keyphrases

end stage renal disease
induced apoptosis
newly diagnosed
ejection fraction
prognostic factors
cell proliferation
single cell
patient reported outcomes
antiretroviral therapy
cell death
patient reported
combination therapy