Elongation of the developing spinal cord is driven by Oct4-type transcription factor-mediated regulation of retinoic acid signaling in zebrafish embryos.
Tatsuya YuikawaTakehisa SatoMasaaki IkedaMomo TsuruokaKaede YasudaYuto SatoKouhei NasuKyo YamasuPublished in: Developmental dynamics : an official publication of the American Association of Anatomists (2023)
The involvement of pou5f3 in spinal cord extension was supported by using mutants and the gain-of-function approach. Our findings further suggest that pou5f3 regulates the RA level, contributing to neurogenesis in the posterior neural tube.