Keratinization in atypical glandular cell clusters as a cytological clue to endometrioid carcinoma on cervical cytology.
Joanna K M NgJoshua Jing Xi LiPublished in: Cytopathology : official journal of the British Society for Clinical Cytology (2023)
Histologic and cytologic keratinization are observed in endometrioid endometrial carcinomas. Such is reflected in cervical cytology by the presence of orangeophilic, rigid and acellular fragments within or associated with AGC clusters. Keratinization, when identified with AGCs, should be regarded as a cytologic clue suggestive of an endometroid carcinoma of endometrial origin.