Radiomics as prognostic factor in brain metastases treated with Gamma Knife radiosurgery.

Chih-Ying HuangCheng-Chia LeeHuai-Che YangChung-Jung LinHsiu-Mei WuWen-Yuh ChungCheng-Ying ShiauWan-Yuo GuoDavid Hung-Chi PanSyu-Jyun Peng

Published in: Journal of neuro-oncology (2020)

The zone percentage of brain metastases, a radiomic feature derived from pre-GKRS contrast-enhanced T1-weighted MRIs, was found to be an independent prognostic factor of local tumor control following GKRS in patients with non-small cell lung cancer and brain metastases. Radiomic features indicate the biological basis and characteristics of tumors and could potentially be used as surrogate biomarkers for predicting tumor prognosis following GKRS.

Keyphrases

brain metastases
prognostic factors
contrast enhanced
small cell lung cancer
magnetic resonance imaging
diffusion weighted
magnetic resonance
computed tomography
diffusion weighted imaging
deep learning
squamous cell carcinoma