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Association between central serous chorioretinopathy susceptibility genes and choroidal parameters.

Kazuya MorinoMasahiro MiyakeTakuro KameiTakahisa KawaguchiYuki MoriYoshikatsu HosodaAkihito UjiKenji YamashiroFumihiko MatsudaAkitaka Tsujikawa
Published in: Japanese journal of ophthalmology (2022)
CFH, VIPR2, TNFRSF10A, and GATA5 showed different association patterns with choroidal parameters. Although the mechanism of CSC pathogenesis by choroidal changes is not fully understood, this finding suggests that each gene may be involved in different mechanisms of CSC development. Our genetic study provides a basis for understanding the role of CSC susceptibility genes.
Keyphrases
  • genome wide
  • optical coherence tomography
  • genome wide identification
  • age related macular degeneration
  • copy number
  • transcription factor
  • dna methylation
  • optic nerve
  • genome wide analysis
  • high grade
  • gene expression