SMAD4 protein is decreased in the dorsolateral prefrontal and anterior cingulate cortices in schizophrenia.

Andrew S Gibbons Daniel Hoyer Brian Dean

Published in: The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry (2020)

Our finding of lower SMAD4 protein in the cortex suggests there are likely to be abnormalities in cortical TGFB-superfamily signalling in schizophrenia.

Keyphrases

bipolar disorder
functional connectivity
working memory
epithelial mesenchymal transition
transforming growth factor
transcranial magnetic stimulation
amino acid
binding protein
prefrontal cortex
high frequency
transcription factor