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Identification and characterization of a novel antifungal compound tubeimoside I targeting cell wall.

Qiannan LiuZhiqi ZhongShunxin ZhengYunzhuo ChuNorihiro SakamotoTakayoshi KunoYue Fang
Published in: Microbiology spectrum (2024)
. Notably, we presented multiple evidence that TBMS1 exerts its antifungal activity through targeting fungal cell walls. Moreover, we verified the antifungal activities of TBMS1 against several pathogenic fungi. Our work indicated that TBMS1 may serve as a novel antifungal candidate, which provides an important foundation for designing and developing new cell wall-targeting agents for combating life-threatening fungal infections.
Keyphrases
  • cell wall
  • candida albicans
  • cancer therapy
  • drug delivery
  • mesenchymal stem cells
  • bone marrow