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MTL-P300 as a marker of the epileptogenic zone and hippocampal functionality in the presurgical evaluation of temporal lobe epilepsy: a systematic review.

Daniela de Andrade MorangeMartha Silvia Martinez-SilveiraMagali Teresópolis Reis AmaralAgnès Trebuchon
Published in: Arquivos de neuro-psiquiatria (2022)
There is evidence that the reduced amplitude of the MTL-P300 has high specificity in identifying the EZ, and this is a good marker for diagnosis in unilateral TLE. The low sensitivity and negative likelihood ratios negative that a normal MTL-P300 response does not exclude the epileptogenicity of the hippocampus.
Keyphrases
  • temporal lobe epilepsy
  • cerebral ischemia
  • resting state
  • cognitive impairment
  • structural basis
  • functional connectivity
  • prefrontal cortex