Astaxanthin attenuates hepatic damage and mitochondrial dysfunction in non-alcoholic fatty liver disease by up-regulating the FGF21/PGC-1α pathway.

Liwei WuWenhui MoJiao FengJingjing LiQiang YuSainan LiJie ZhangKan ChenJie JiWeiqi DaiJianye WuXuanfu XuYuqing MaoChuan-Yong Guo

Published in: British journal of pharmacology (2020)

Astaxanthin attenuated hepatocyte damage and mitochondrial dysfunction in NAFLD by up-regulating FGF21/PGC-1α pathway. Our results suggest that astaxanthin may become a promising drug to treat or relieve NAFLD.

Keyphrases

skeletal muscle
oxidative stress
liver injury
emergency department
drug induced
liver fibrosis