Cardenolide-rich fraction of Pergularia tomentosa as a novel Antiangiogenic agent mainly targeting endothelial cell migration.

Mahya HosseiniMahdi AyyariAnna MeyfourSonia PiacenteAntonietta CerulliAlexander CrawfordSara Pahlavan

Published in: Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences (2020)

Thus, the P. tomentosa cardenolide-rich fraction (PtR2) may hold a considerable promise for an antiangiogenic impact by impairment of endothelial cell (EC) migration and viability. Graphical abstract.

Keyphrases

cell migration
endothelial cells
cancer therapy
high glucose
big data
deep learning
artificial intelligence