Injury Severity is a Key Contributor to Coagulation Dysregulation and Fibrinogen Consumption.
Andrew R GosselinChristopher G BargoudAbhishek SawalkarShane MathewAshley ToussaintMatthew GreenenSusette M CoyleMarie MacorAnandi KrishnanJulie GoswamiJoseph S HannaValerie TutwilerPublished in: bioRxiv : the preprint server for biology (2024)
Traumatic injury may lead to alterations in a patient's ability to form stable blood clotsA study was performed to assess how trauma severity affects coagulation kineticsKey alterations were observed in trauma patients, who exhibit weaker and slower forming clotsPaired with machine learning methods, the results indicate key aspects contributing to mortality.